Giardia lamblia : loss of the CRP 170 gene
نویسنده
چکیده
in an antigenic variant. Giardia lamblia: loss of the CRP170 gene The cysteine-rich protein gene family of
منابع مشابه
Detection of Giardia lamblia Cysts in Surface Waters of Rasht City, Iran
Introduction: Giardia lamblia is a protozoan parasite with universal distribution in human populations. This infections transfer to human via contaminated foods and waters with Giardia cysts. The Knowledge on the incidence of this agent in the potential infection sources can provide valuable information for control and the spread of this parasite to human communities. This study was aimed to is...
متن کاملAntigenic variation of a cysteine-rich protein in Giardia lamblia
The WB isolate of Giardia lamblia expresses a cysteine-rich 170-kD surface antigen (CRP170) that undergoes antigenic variation. An (6E7), cytotoxic for isolates expressing CRP170, was used in another study to select antigenic variants from clones of the WB isolate of Giardia. CRP170 was replaced by surface-labeled bands ranging in size from approximately 50 to 170 kD. In this study, mAb 6E7 was...
متن کاملThe comparison of “tim” gene of Giardia lamblia in laboratory animals and human and the importance of cross transmission probability in Iran
BACKGROUND: Giardia has the ability to infect many mammals including dogs, cats, deer, mice, ground squirrels, chinchillas, swine, rabbits, pocket mice, oxen, guinea pigs, and humans. Giardia lamblia (also Giardia duodenalis, G.intestinalis) isolates have been variably divided into two or three genotypes by different investigators, and each group can be divided into subgroups. OBJECTIVES: We ha...
متن کاملSecretory immune response to membrane antigens during Giardia lamblia infection in humans.
The secretory immune response in humans infected with Giardia lamblia was studied by using saliva samples and a membrane-rich protein fraction. The membrane fraction, studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, showed 24 antigen bands, ranging from 170 to 14 kDa. Saliva samples from giardiasis patients showed a heterogeneous response against the membrane fraction when ...
متن کاملAntigenic variation of Giardia lamblia in vivo.
A single Giardia lamblia trophozoite can give rise in vitro to G. lamblia with varying surface antigens. To determine whether antigenic variation also occurs in vivo, gerbils were inoculated with defined G. lamblia clones and the surface antigens of the intestinal trophozoites were studied at different times during the infection. The proportion of monoclonal antibody 6E7-reacting trophozoites f...
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